# David Greenhalgh

Professor

### Personal Statement

I gained a PhD from the University of Cambridge in 1984 and worked at Imperial College, London from 1984 to 1986. I also have a first class Honours degree in Mathematics and a distinction in Part III Mathematics. I am currently a member of the Population Modelling and Epidemiology Research Group at Strathclyde and have been a member of Strathclyde in the Departments of Mathematics, Statistics and Modelling Science and Mathematics and Statistics since 1986. I am currently Fourth Year Adviser of Studies and also Executive Editor of Journal of Biological Systems.

In 2015 I was awarded a two year (2015-2017) Leverhulme Trust Research Fellowship grant (50K RF-2015-88) as PI to study mathematical modelling of vaccination against dengue.

### Expertise & Capabilities

I have expertise in mathematical and statistical modelling applied to biological problems, using differential equations to model biological problems, mathematical analysis, stochastic analysis, stochastic differential equations, maximum likelihood estimation and R software.

I have also taught many courses in the area of mathematics and statistics and supervised or co-supervised many undergraduate and postgraduate projects in mathematics and statistics.

### Research Interests

My research interests involves mathematical and statistical techniques applied to biological problems, in particular mathematical and statistical modelling in epidemiology. I have over eighty papers in high quality refereed journals and have supervised or co-supervised almost twenty research students, seventeen at PhD level. I am regularly invited to speak at international conferences including as keynote and plenary speaker. Application areas of interest include HIV/AIDS, both heterosexual spread and spread amongst intravenous drug users, dengue vaccination, hepatitis A, hepatitits C, mumps and rubella. I have extensive overseas collaborations including Brazil (Professor E. Massad), India (Professor J. Chattopadhyay), Oman (Professor Q. J. A. Khan), Germany and The Netherlands.

In 2015 I was awarded a two year (2015-2017) Leverhulme Trust Research Fellowship grant (50K RF-2015-88) as PI to study mathematical modelling of vaccination against dengue.

### Industrial Relevance

I have worked in collaboration with Health Protection Scotland (mathematical modelling of the spread of pneumococcus and the introduction of new pneumococcus vaccines, mathematical modelling of the spread of hepatitis C and hepatitis C control strategies such as needle cleaning and needle exchange and the effect of heterogeneity). I have also been involved in the development of a statistically based algorithm for infectious disease outbreak reporting which formed the basis of the system currently used by Health Protection Scotland. I have worked as a consultant for Public Health England where I was involved in identifying and quantifying replication in anonymous HIV test databases.

I have also worked with Wyeth vaccines on developing new vaccines for pneumococcus. and with Capita on statistical analysis of telephone call centre data.

### Teaching Interests

My current teaching includes

**MM111 Mathematics 1B**

Teaches basic mathematics, foundations, calculus and complex numbers to engineering students.

**MM114 Engineering Mathematics 2E**

Teaches basic mathematics, calculus, geometry and vectors, matrices and numerical methods to engineering students.

**MM118 Foundation Statistics.**

Teaches basic statistics, data presentation, probability, hypothesis testing, confidence intervals, regression, correlation and association to bioscientists.

**MM304 Inference and Regression Modelling.**

Teaches statistical inference and advanced regression technques to mathematically based degree students.

## Publications

(59)## Analysis of the optimal vaccination age for Dengue in Brazil with a tetravalent Dengue vaccine

Research output: Research - peer-review › Article

## Estimating the prevalence of infectious diseases from under-reported age-dependent compulsorily notification databases

Research output: Research - peer-review › Article

## Modelling the impact of the long-term use of insecticide treated bednets on Anopheles mosquito biting time

Research output: Research - peer-review › Article

## Activities

(172)## Measuring unrecognised replication present in HIV databases.

Activity: Talk or presentation › Invited talk

## Workshop on Mathematical Modelling, International Medical University, Kuala Lumpur, Malaysia.

Activity: Participating in or organising an event › Participation in conference

## Dengue Seminar and Round Table Discussion

Activity: Participating in or organising an event › Key-note speaker and plenary lectures at conferences

## Projects

(13)## EPSRC Institutional Sponsorship: Global Challenges Research Fund (GCRF) / R160677-105

Project: Research - Internally Allocated › Research (Internally Allocated)

## Mathematically Modelling Dengue Vaccination

Project: Non-funded project

## Mathematically Modelling the Risk of Zika Virus to Tourists to Brazil

Project: Internally funded project

## Impact

(1)## Health and cost benefits of monitoring infectious diseases using novel statistical methods.

Impact: Impact - for External Portal › Economic and commerce, Health and welfare - new products, guidelines and services