Revolutionizing prokaryotic systematics through next-generation sequencing

Research output: Chapter in Book/Report/Conference proceedingChapter

Next-generation sequencing has revolutionized modern research in all life sciences. It has been applied in studying evolution, global transmission and local adaptation of pathogens, microbial ecology, genetics and physiology. In this chapter, we have provided a brief summary of recent advances in sequencing technologies and easy to use bioinformatic tools to analyse sequence data, with a focus on prokaryotic biology. We have emphasized the importance of routinely applying whole genome sequencing in prokaryotic systematics, evolution, genotyping and functional characterization.

Original languageEnglish
Title of host publicationNew Approaches to Prokaryotic Systematics
EditorsMichael Goodfellow, Iain Sutcliffe, Jongsik Chun
Pages75-101
Number of pages27
DOIs
StatePublished - 28 Aug 2014

Publication series

NameMethods in Microbiology
PublisherElsevier
Volume41

    Research areas

  • bioinformatic tools, comparative genomics, de novo assembly, genome annotation, mapping, next-generation sequencing, phylogenetic analyses, prokaryotic systematics
  1. Comparative genomics of Pseudomonas aeruginosa

    Activity: Talk or presentationInvited talk

  2. Comparative genomics of Pseudomonas aeruginosa

    Activity: Talk or presentationInvited talk

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