Installation ofthe StrathE2E model De-compress the StrathE2E_Public.zip file, with setting to recreate the original folder structure. You should have the following folder structure StrathE2E_Public /Driving data /library /parameters /results /Target data StrathE2E_Public should contain two files PROG_OCE_E2E_MODEL_RELEASE.R Script to run the model ANNEALING_PROG_OCE_E2E_MODEL_RELEASE.R Script to fit model parameters There is a long section of introduction and explanation in the header of each script file If you are a Windows user, towards the top of these scripts wou will find the lines path <- "C:/Users/ais04103/Documents/D/E2E_ecomodel/code/StrathE2E_Public/" drivingpath <- paste(path,"Driving data/",sep="") oudir <- paste(path,"results/",sep="") You need to set the path to the location where you extracted the folder StrathE2E_Public As well as installing R, if you are running under Windows you need to install RTools https://cran.r-project.org/bin/windows/Rtools/ Regardless of operating system, you will also need the package deSolve https://cran.r-project.org/web/packages/deSolve/index.html Then, just open an R command window and either: Copy and paste the contents of one of the script files into the command window or Set the working directory to the path above, and type ... source("PROG_OCE_E2E_MODEL_RELEASE.R") Should all run fine.